ESTROKAD®
ABOUT BRAND
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Brand name:
ESTROKAD®
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Dosage form:
Vaginal suppositories
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Composition:
Active pharmaceutical substance: estriol – 0,50 mg.
Excipients: solid fat (vitepsol S51), macrogol cetostearyl ether, glyceryl monoricinoleate.
Topical hormonal medicine (estriol) for the atrophic vaginitis treatment due to menopause.
Description
White homogeneous suppositories, odorless. On a longitudinal slice the suppository is a homogeneous mass, without layers, containing no inclusions.
Indications
— Menopausal hormone therapy (MHT): treatment of lower urinary and genital tract mucosal atrophy associated with estrogen deficiency in postmenopausal women
— Pre- and postoperative therapy for postmenopausal women undergoing vaginal access surgery
— As a diagnostic aid in obtaining an atrophic cervical smear pattern
Counterindications
— Hypersensitivity to estriol and/or to any of the excipients of the preparation
— Diagnosed, history of, or suspected breast cancer (BC)
— Diagnosed or suspected estrogen-dependent tumors (e.g., endometrial cancer)
— Vaginal bleeding of unclear etiology
— Untreated endometrial hyperplasia
— Current or history of venous thromboembolism (VTE) (deep vein thrombosis, pulmonary embolism)
— Confirmed thrombophilic disorders (e.g., protein C, protein S or antithrombin III deficiency, etc.)
— Arterial thrombosis or thromboembolism (ATE), including myocardial infarction, stroke, cerebrovascular disorders, or prodromal states, including transient ischemic attack, angina pectoris
— Acute liver disease or a history of liver disease after which liver function tests have not returned to normal
— Porphyria
— Pregnancy and breastfeeding
The entire list of counterindications can be found in the medicine`s instruction.